SH3 library
All SH3-Domain Phager:
Detect specific human SH3 domain interactions for your protein of interest.
Our ready-to-use assay provides:
- Fast and unbiased detection of binding targets from a pool of more than 300 human SH3 domains
- Entire selection of individual SH3 domains which bind your specific ligand
- High specificity guaranteed due to lack of spurious interference from other non-target proteins
- Applicable to any target protein
- Easy association of selected SH3 domains to corresponding protein via accession number
Our All SH3-Domain Phager is the only assay available for an easy and simultaneous screening of the complete human SH3 proteome for interaction partners of your protein.
References:
- Tapio Kesti, Anja Ruppelt, Jing-Huan Wang, Michael Liss, Ralf Wagner, Kjetil Taskén and Kalle Saksela
Reciprocal Regulation of SH3 and SH2 Domain Binding via Tyrosine Phosphorylation of a Common Site in CD3
The Journal of Immunology, 2007, 179: 878-885.
- Kärkkäinen S, Hiipakka M, Wang JH, Kleino I, Vaha-Jaakkola M, Renkema GH, Liss M, Wagner R, Saksela K. (2006)
Identification of preferred protein interactions by phage-display of the human Src homology-3 proteome.
EMBO Rep. 2006 Feb;7(2):186-91.
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