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SH3 Phage Display Library

 

All SH3-Domain Phager:

Detect specific human SH3 domain interactions for your protein with interest.

Our ready-to-use assay provides:

  • Fast and unbiased detection of binding targets from a pool of all known 288 human SH3 domains
  • Entire selection of individual SH3 domains which bind your specific ligand
  • High specificity guaranteed due to lack of spurious interference from other non-target proteins
  • Applicable to any target protein
  • Easy association of selected SH3 domains to corresponding protein via accession number

Our All SH3-Domain Phager is the only assay available for an easy and simultaneous screening of the complete human SH3 proteome for interaction partners of your protein.

 

References:

  • Tapio Kesti, Anja Ruppelt, Jing-Huan Wang, Michael Liss, Ralf Wagner, Kjetil Taskén and Kalle Saksela
    Reciprocal Regulation of SH3 and SH2 Domain Binding via Tyrosine Phosphorylation of a Common Site in CD3
    The Journal of Immunology, 2007, 179: 878-885.

  • Kärkkäinen S, Hiipakka M, Wang JH, Kleino I, Vaha-Jaakkola M, Renkema GH, Liss M, Wagner R, Saksela K. (2006)
    Identification of preferred protein interactions by phage-display of the human Src homology-3 proteome.
    EMBO Rep. 2006 Feb;7(2):186-91.

 

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